Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. Maleic anhydride is a colorless to white solid that forms orthorhombic crystals and decomposes in water. NCI [1974]. ], inhalation, ingestion, skin and/or eye contact, irritation nose, upper respiratory system; conjunctivitis; photophobia (abnormal visual intolerance to light), double vision; bronchial asthma; dermatitis, Centers for Disease Control and Prevention. 5. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA safety hazards of Maleic Acid to potentially exposed workers. Causes skin burns. +86-532-8027466 SECTION 1: PRODUCT AND COMPANY IDENTIFICATION ... Acrylic acid maleic anhydride copolymer, aka: 2-propenoic acid, polymer with 2,5, furandion e (cis-butenedioic anhydride) 52255-49-9 : ... Acrylic Acid Maleic … Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. May cause digestive tract (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. May cause allergic skin and respiratory reaction. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Hazard classification & labelling Hazard classification and labelling. 108 -31 -6 203 -571 -6 607 -096 -00 -9 - 4. MCA [1974]. Maleic anhydride has several uses, almost all of them related to the synthesis of other chemicals as fumaric and tartaric acids, certain agricultural chemicals (i.e., maleic hydrazide, malathion), lubricants, surface active agents, resins in different products, dye intermediates, pharmaceuticals, and more. exposure may cause allergic respiratory reaction (asthma). Maleic anhydride undergoes a potentially explosive exothermic Diels-Alder reaction with 1-methylsilacyclopenta-2,4-diene at 150C [Barton, T. J., J. Organomet. Causes gastrointestinal tract burns. Maleic anhydride is used in the formulation of resins. Stir the mixture for 10 min. Safety Statements :26-36/37/39 Causes chemical burns to the respiratory tract. skin. When heated to decomposition it emits acrid smoke and irritating vapors. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Rinse mouth with water (only if the person is conscious). The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. tract irritation and possible burns. May cause blistering of the skin. SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. May cause asthmatic attacks due to allergic sensitization of the Reproductive Toxicity: No data available Reproductive toxicity - Rat - Oral Maleic anhydride CAS -No. Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. Add 0.98 g (0.01 mole) of maleic anhydride to a solution of 1.67 g (0.01 mole) of veratrylamine in 10 mL of chloroform. Causes respiratory Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. National Cancer Institute, June 17, 1974. (2) Conversion Factors: The odour warning when the exposure limit value is exceeded is insufficient. Safety Data Sheet (Maleic Anhydride) DATE PREPARED: 9/3/2015 Page 7 of 9 OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified as a carcinogen or potential carcinogen by OSHA. System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Common Name Maleic Anhydride Synonym(s) 2,5Furandione Formula C 4 H 2 O 3 CAS Number 108316 COMPONENT CAS NUMBER CONCENTRATION Maleic Anhydride 108316 ≤ Section 4. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. May cause conjunctivitis. Dissolve the residue in a minimal amount of chloroform. Risk Statements: 36/37/38 R36/37/38:Irritating to eyes, respiratory system and skin. Inhalation: irritation with nausea, vomiting, and diarrhea. Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. pain. If not breathing, give artificial respiration. reaction, which becomes evident upon re-exposure to this material. Immediate medical attention is required. respiratory tract. Environmental: Maleic anhydride's fate in soil is unknown. double vision, and "halo" vision. Show this safety data sheet to the doctor in attendance. Causes redness and pain. Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F Remove victim to fresh Recrystallize the maleic anhydride from toluene. Causes redness and Move out of dangerous area. Causes eye burns. Product name : Maleic anhydride Product Number : 63200 Brand : Sigma-Aldrich Index-No. Combustible Solid, but may be difficult to ignite. Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. Wash out mouth with water. Maleic acid 110-16-7 >95 4. "Maleic Anhydride, Maleic Acid, and Fumaric Acid." : 607-096-00-9 CAS-No. Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. EC -No. Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Consult a physician. Inhalation of high concentrations may cause pulmonary edema. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 none Water, Foam, Alcohol resistant foam, ABC-powder Water jet Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2) In … Target Organs: Lungs, respiratory system, eyes, Eye: Wear safety goggles or eye protection in combination with breathing protection if powder. Harmful if swallowed. MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9974 If inhaled If breathed in, move person into fresh air. 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