Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. It is available in brand and generic form. More common side effects. Read this article to learn more about dosage and side effects. O 0. 2. Ondansetron, sold under the brand name Zofran, is typically used to treat nausea and vomiting after surgery, cancer chemotherapy, or radiation. "Product Information. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, A Condition Where The Body Is Unable To Maintain Adequate Blood Flow Called Shock, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome, A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis, A Type Of Allergic Reaction Called Angioedema, Extrapyramidal Disease, A Type Of Movement Disorder, Painful And Involuntary Movement Of The Eyes Called Oculogyric Crisis, Torsades De Pointes, A Type Of Abnormal Heart Rhythm, An Inability To Completely Empty The Bladder. Side Effects. Slow Heartbeat 14. Giant Hives 10. It is available in both brand and generic form. Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. Zofran is a drug with problematic side effects. Zuplenz (ondansetron)." Common side effects of Zofran include headache, feeling unwell (malaise), fatigue, drowsiness, constipation, dizziness, and diarrhea. © 2005 - 2019 WebMD LLC. Selected from data included with permission and copyrighted by First Databank, Inc. Strativa Pharmaceuticals, a Division of Par Pharmaceuticals, Inc., Woodcliff Lake, NJ. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. "Product Information. In the ondansetron prescribing label information (Zofran®, Zofran ODT® package insert), the most commonly reported ondansetron (Zofran®, Zofran ODT®) side effects are shown here. Most side effects of Zofran are mild or moderate, but some may be severe or life-threatening. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to ondansetron: injectable solution, intravenous solution, oral disintegrating strip, oral solution, oral tablet, oral tablet disintegrating, The most frequently reported side effects are headache, constipation, and diarrhea. Zofran is available in generic form. Common side effects associated with Zofran include headache, drowsiness, constipation and the chills. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Zofran Side Effects Include Injuries to Mothers and Babies. Side effects. WebMD does not provide medical advice, diagnosis or treatment. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron orally disintegrating tablet may cause drowsiness. If experienced severely or for a … Unlike some other nausea medicines, the side effects for Zofran (ondansetron… The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The National Institutes of Health lists the following as common side effects. Cerner Multum, Inc. "Australian Product Information." [Ref], Common (1% to 10%): Sensation of warmth/flushing, bradycardia, hypotension, arrhythmias, Uncommon (0.1% to 1%): Chest pain with/without ST segment depression, Rare (0.01% to 0.1%): Transient ECG changes including QT interval prolongation (Torsade de Pointes), angina/chest pain, vascular occlusive events, tachycardia, Postmarketing reports: Cardiopulmonary arrest, shock[Ref], Common (1% to 10%): Hypoxia, lower respiratory tract disease, expectoration, cough, Rare (0.01% to 0.1%): Bronchospasm/asthma, Postmarketing reports: Shortness of breath, laryngeal edema, stridor, laryngospasm[Ref], Laryngospasm occurred during allergic reactions in patients given the IV formulation. It is also effective for treating gastroenteritis. [Ref], Wound problems occurred at the surgical site in patients given this drug for the treatment of postoperative nausea and vomiting. Transient, asymptomatic increases in AST/ALT 2 times the upper limit of normal commonly occurred in patients receiving chemotherapy with cisplatin, and did not appear to be related to dose/duration of treatment. Dizziness occurred during rapid IV administration. We comply with the HONcode standard for trustworthy health information -. Oculogyric crisis occurred alone and in combination with other dystonic reactions. Toxic Epidermal Necrolysis 17. Zofran Side Effects When given to a pregnant woman, Zofran can cause a wide range of birth defects. Shock 13. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. 3. [Ref], Very common (10% or more): Headache (up to 27%), drowsiness/sedation (up to 23%), Common (1% to 10%): Dizziness, paresthesia, Uncommon (0.1% to 1%): Seizures, movement disorders/extrapyramidal reactions (oculogyric crisis/dystonic reactions, dyskinesia), Rare (0.01% to 0.1%): Grand mal seizures[Ref]. What Are Side Effects of Zofran? Some of the dosage forms listed on this page may not apply to the brand name Zofran. Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer chemotherapy and also used to prevent and treat nausea and vomiting after surgery. Fast Heartbeat 9. difficulty with passing urine (dribbling), puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased blinking or spasms of the eyelid, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, uncontrolled twisting movements of the neck, trunk, arms, or legs, difficulty having a bowel movement (stool), uncontrolled movements, especially of the face, neck, and back, redness of the face, neck, arms, and occasionally, upper chest. There are some side effects associated with Zofran. [Ref], Very common (10% or more): Wound problem (up to 28%), malaise/fatigue (up to 13%), Common (1% to 10%): Shivers, pyrexia/fever, cold sensation, Frequency not reported: Pain, ear disorder[Ref], Very common (10% or more): Diarrhea (up to 16%), constipation (up to 11%), Common (1% to 10%): Xerostomia, nausea, vomiting, localized anal/rectal burning sensation, Frequency not reported: Gastric symptoms, abdominal pain, flatulence[Ref], Localized anal/rectal burning occurred after insertion of the suppository formulation.[Ref]. Cerner Multum, Inc. "UK Summary of Product Characteristics." The most concerning side effects of Zofran include effects on the heart rhythm, a potential for birth defects and a condition known as serotonin syndrome. Effective use during pregnancy is an issue in Canada as well consult your healthcare provider to the. Consult your healthcare provider to ensure the information displayed on this page applies to:. 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